You'll find more commentary on recent research into advanced glycation endproducts (AGEs) and alagebrium over at Ouroboros: ''A drug was designed against a specific form of age-related damage, demonstrated to attack this damage in vitro, and then shown to be efficacious in a clinical setting. In addition to providing good news for sufferers of ...

Alagebrium, or ALT-711, is an AGE-breaker - a class of compound designed to break up the advanced glycation endproducts (AGEs) that contribute to some types of age-related degeneration. ''Arterial stiffening and endothelial dysfunction are hallmarks of aging, and advanced glycation endproducts (AGE) may contribute to these changes. We tested the ...

An interesting article on the state of glycosylation biochemical engineering can be found at Chemical & Engineering News. A great deal of expertise and practice in the use of biochemistry to perform and reverse glycation reactions exists, by the look of it. ''Carbohydrate chemists and biochemists tend to be controlling personalities. They aren't ...