Scientist David Sinclair holds forth on metabolism, aging, calorie restriction and his research at Newsweek: ''About 70 years ago, scientists discovered that when animals are forced to live on 30 to 40 percent fewer calories than they would normally eat, something unusual happens: they become resistant to most age-related diseases - cancer, heart ...

Via Forbes, another study attempting to tease out the mechanisms by which calorie restriction affects metabolism and health: ''Lowering the core body temperature of mice let them live an average of 15 percent longer ... It was known in animals that calorie restriction is associated with reduction of the core body temperature. It was not known if ...