From the open access journal Immunity & Aging: ''The term ''Inflammaging'' has been coined by Claudio Franceschi to explain the now widely accepted phenomenon that ageing is accompanied by a low-grade chronic, systemic up-regulation of the inflammatory response and that the underlining inflammatory changes are also common to most age-associated ...

''Inflammaging'' is a packaging of the present understanding of the way in which chronic inflammation and a failing immune system interact to contribute to degenerative aging. From this paper: ''A large part of the aging phenotype, including immunosenescence, is explained by an imbalance between inflammatory and anti-inflammatory networks, which ...

Medical News Today reminds us of the link between excess fat, inflammation, and earlier onset of age-related disease: ''a high fat diet draws inflammatory cells into fat tissue, which prevents the tissue from storing the fats we eat. When the tissue can not store these fats, they end up in the liver and muscle, which in turn causes diabetes and ...

Blood vessels harden with age, causing a variety of dangerous conditions related to high blood pressure. This has been linked to advanced glycation endproducts (AGEs); here, EurekAlert reports on a different viewpoint: ''The research, which was done in test tubes and animal models, needs to be confirmed in humans before it could form the basis for ...

The ''inflammaging'' meme is gaining traction as illustrated by this review paper (even if no-one can agree on the spelling). ''In this article we summarise present knowledge on the role of pro-inflammatory cytokines on chronic inflammation leading to organismal aging, a phenomenon we proposed to call ''inflamm-aging''. ... On the whole, despite ...

The second Living Well to 100 conference will be held in Boston in November of this year: ''We have brought together an outstanding group of experts to explore the theme, 'Is Inflammation Central to Aging?' As with the first Living Well to 100 Conference, we will focus on wellness and how to keep healthy people well for a greater portion of their ...