Scientists in Spain and Italy have identified a group of proteins in laboratory rats that could help explain two enduring medical mysteries why women live longer than men and why calorie restriction stands as the only proven method of extending longevity. Their study, which could help scientists understand the biochemical underpinnings of aging, ...

A study investigating aging in mice has found that hormonal changes that occur when mice eat significantly less may help explain an already established phenomenon: a low calorie diet can extend the lifespan of rodents, a benefit that even regular exercise does not achieve. “We know that being lean rather than obese is protective from ...

Dr. Laura Dugan, Departments of Medicine & Neurosciences at UCSD, discusses what we have learned about the aging process from lower organisms, and what is known to date about humans and calorie restriction. Targeted dietary approaches such as calorie restriction have the potential to contribute to a longer “health span” and to successful ...

Channel 4 Documentary following the revolutionary life-extension and immortality ideas of this somewhat eccentric scientist, Dr. Aubrey de Grey. This show is all about the radical ideas of a Cambridge biomedical gerontologist called Aubrey de Grey who believes that, within the next 20-30 years, we could extend life indefinitely by addressing ...

Another round of calorie restriction research from PLoS Medicine: ''Caloric restriction without malnutrition extends life span in a range of organisms including insects and mammals [and] delays the onset of age-related chronic diseases such as heart disease and stroke. There are also hints that people who eat a calorie-restricted diet might live ...

Via Forbes, another study attempting to tease out the mechanisms by which calorie restriction affects metabolism and health: ''Lowering the core body temperature of mice let them live an average of 15 percent longer ... It was known in animals that calorie restriction is associated with reduction of the core body temperature. It was not known if ...