This is the untold story of how the global racket in fake drugs turned an easily curable disease into Africa’s biggest child killer. According to leading scientists, millions of children could have been saved if the pharmaceutical industry and World Health Organisation had collaborated to address the problem. Now, signs are emerging that malaria is developing resistance to the one effective drug which can still treat it. It’s a development which threatens patients all over the world. But - after decades of silence - has the WHO left it too late to act?
From ScienceDaily...
Discovery may eradicate malaria
TROY, N.Y., Aug. 29 (UPI) -- U.S. scientists have identified a key link that causes malarial infections in both humans and the mosquitoes that transmit the disease.
Rensselaer Polytechnic Institute scientists who led the study said if that link in the chain of infection can be broken at its source -- the mosquito -- then the spread of malaria could be stopped without anyone needing to a take a drug.
The team found both humans and mosquitoes share the same complex carbohydrate, heparan sulfate, that's a receptor for the malaria parasite, binding to the parasite and giving it quick and easy transport through the body.
"The discovery allows us to think differently about preventing the disease," said Professor Robert Linhardt, who led the study. "If we can stop heparan sulfate from binding to the parasite in mosquitoes, we will not just be treating the disease, we will be stopping its spread completely."
The research, which included doctoral students Melissa Kemp and Jin Xie, as well as New York University entomologist Dr. Photini Sinnis, is to be published in the Journal of Biological Chemistry.
Copyright 2007 by United Press International. All Rights Reserved.