First the good news: a study by scientists at the Buck Institute for Age Research shows four common antioxidants extended lifespan in the nematode worm C. elegans. And the not such good news: those four were among 40 antioxidants tested, the majority of which did nothing or caused harm to the microscopic worms.

The findings highlight the complexity of biological processes involved in aging and sends a cautionary signal to consumers who take antioxidants assuming the supplements will help them live longer, healthier lives. Results of the study now appear in the online edition of Experimental Gerontology.

In 2000, Buck Institute scientists made the landmark discovery that a chemical compound could extend the lifespan of simple animals. This discovery fuelled speculation that human lifespan could be extended with similar antioxidant compounds. In this follow up study, the scientists chose antioxidants readily available at health food stores along with those commonly used by chemists in various skin care or food products. The four which extended lifespan (by 15% - 20%) in the nematodes are Lipoic acid, Propyl gallate, Trolox and Taxifolin.  Read More...