Stem cells’ powers of self-renewal, immortality and
potential for medicine inspire those who study them. But progress toward
understanding them has been slow — it took 20 years just to figure
out how to grow embryonic stem cells in the laboratory. More recently, though,
molecular techniques have enabled swift movement on two fronts. Researchers are
starting to see how stem cells can replenish their numbers while giving rise to
specialized cells. Others are learning how to turn adult skin cells into cells
more like their embryonic ancestors. These advances offer hope that scientists
will soon harness the capabilities of stem cells, at last fulfilling the cells’
promise.
Reverting adult cells to an embryonic state without creating
embryos is a tricky business
The diagnosis is not good; the patient will need surgery. So
the doctor plucks a hair from the patient’s head and tells her to come back in
a few weeks. When the patient returns, the surgeon patches up the faulty organ
by implanting healthy cells generated in the lab from the patient’s hair
follicle. After a few months, the new cells have integrated into the organ and
the woman’s symptoms recede. A year later, she’s healthy and living a normal
life. Read More...