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Green tea compounds beat OSA-related brain deficits

Researchers examined the effects green tea polyphenols (GTP), administered through drinking water, on rats who were intermittently deprived of oxygen during 12-hour “night” cycles, mimicking the intermittent hypoxia (IH) that humans with OSA experience.

People with OSA have been reported to have increased markers of oxidative stress and exhibit architectural changes in their brain tissue in areas involved in learning and memory. Chronic IH in rats produce similar neurological deficit patterns.

“OSA has been increasingly recognized as a serious and frequent health condition with potential long-term morbidities that include learning and psychological disabilities […],” wrote David Gozal, M.D., professor and director of Kosair Children’s Hospital Research Institute at the University of Louisville, lead author of the article. “A growing body of evidence suggests that the adverse neurobehavioral consequences imposed by IH stem, at least in part, from oxidative stress and inflammatory signaling cascades.”
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Published Friday, May 16, 2008 11:22 AM by clementlawyer

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About clementlawyer

James Clement is currently the Owner of Betterhumans.com. James is also the Executive Director of the World Transhumanist Association, and the President of the InnerSpace Foundation.
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